WHAT IS SETRIA GLUTATHIONE AND WHY IS IT DIFFERENT?

Glutathione is recognized as the great protector. Without glutathione, each cell would become so ravaged by free radicals that it would disintegrate. A lack of glutathione would also negatively affect the liver and immune system. By fighting free radicals, glutathione supports the liver so it can carry out its job of detoxifying the body. Likewise, preventing free radical damage also helps promote a healthy immune system.

Our bodies obtain glutathione in two ways: from the foods we eat and from our own internal production. Because of the body’s ability to make glutathione, it is not considered an “essential” nutrient. Under some conditions, though, the body’s need for glutathione is outpaced by its ability to produce it.

Setria,L-Glutathione or Reduced Glutathione and is superior to other glutathione based on the following features:

Clinically studied to increase blood glutathione levels and support the immune system

A pure and safe material with an assay value of 99.0% – 101.0%

Produced by a patented, fermentation process

Contains no additives, artificial flavors or preservatives

Has no animal origin material (vegetarian)

Meets specification for the new USP monograph (USP)

Meets specification for The Japanese Pharmacopoeia (JP)

No TSE/BSE risk

GMP-compliant manufacturing

Allergen-free

Kosher

ANTIOXIDANT PROPERTIES

How does Setria help your body fight free radicals?

Eating, exercising, even breathing results in the creation of free radicals. These imbalanced molecules attack your body at the cellular level, robbing other molecules of electrons and setting off a chain reaction. This constant barrage impacts overall health and wellness, as well as how quickly you age.Setria supplies a potent store of antioxidants that bind to free radicals, keeping them from wreaking havoc throughout your body.

WHY IS GLUTATHIONE CALLED THE “MASTER ANTIOXIDANT”?

Glutathione does more than simply fight free radicals on its own. This antioxidant also has the ability to regenerate other antioxidants, such as vitamins C and E. After these antioxidants neutralize free radicals, they become unstable radicals themselves. Glutathione helps recycle these unstable molecules, returning them to active duty.

DETOXIFICATION

How does Setria help eliminate toxins?*

Glutathione supports the function of your liver, kidneys, GI tract and intestines—your body’s major detoxification pathways.* Glutathione helps in two main ways:  it helps eliminate toxins and ingested chemicals that the body has already absorbed;it intercepts and neutralizes toxins in the GI tract before they are even absorbed.

IMMUNE HEALTH

How does Setria fortify your immune system?*

Glutathione helps fortify your immune system in two important ways. First and foremost, it plays a central role in the proper function of white blood cells, including T cell lymphocytes—the frontline soldiers of the immune system. Second, there is evidence that glutathione stimulates the natural killing ability 

of immune cells.

Skin Health

Setria is an ultra-pure glutathione manufactured in Japan that is backed by years of research. A high-quality, allergen-free ingredient, Setria is the perfect choice for dietary supplements and beauty products promising to deliver skin care benefits.

How does Setria Glutathione help protect against photo-aging?

UV rays penetrate deeply in to the dermis and can cause premature skin aging by damaging the collagen fibers. Glutathione is a powerful antioxidant that protects the collagen fibers from free radical damage to protect the elasticity of the skin.

How does Setria Glutathione reduce melanin production?

Exposure to UVB increases the number of melanocytes which leads to hyperpigmentation that darkens the skin. It has been reported that glutathione reduces melanin production by suppressing the activity of tyrosinase and switching the eumelanin synthesis to pheomelanin synthesis.

FACTORS AFFECTING GLUTATHIONE STATUS

Your body’s natural glutathione levels fluctuate constantly throughout the day, are lowest in the morning and decrease as you age. Exposure to toxins, ingested and environmental chemicals and even things as healthy as exercise can all increase free radicals and ramp up your body’s need for glutathione.

Time of Day: According to researchers at Emory University, levels of glutathione vary over a 24-hour period, spiking about six hours after each meal and hitting their lowest point in the morning hours.

Age: Young, healthy people tend to have enough glutathione. However, glutathione levels start to decline at around age 45 and continue to decline until death.

Health Conditions: Glutathione status may be depleted by a variety of different health conditions.

Diet: The best dietary sources of glutathione are freshly prepared meats and fresh fruits and vegetables (both raw and cooked). Most processed foods have little to no glutathione.

Glutathione Antagonists: Some foods – such as cereals, bread, and dairy products – are not only lacking glutathione, they actually act as glutathione antagonists. Common beverages such as tea and coffee also contain glutathione -destroying compounds, although in lower concentrations.

Lifestyle Factors: Because cigarette smoking and excessive alcohol intake cause an increase in free radical production, both habits deplete glutathione levels.

Medications: Both prescription and over-the-counter drugs can lower glutathione status.

Weight: People who are overweight tend to have lower glutathione levels than those who are within normal weight range because excess fat is correlated with oxidative (free radical-induced) stress.

SO WHAT CAN YOU DO TO OPTIMIZE YOUR GLUTATHIONE LEVELS?

Consume sulfur-rich foods. The main ones in the diet are garlic, onions and the cruciferous vegetables (broccoli, kale, collards, cabbage, cauliflower, watercress, etc.).

Exercise boosts your glutathione levels and thereby helps boost your immune system, improve detoxification and enhance your body’s own antioxidant defenses. Start slow and build up to 30 minutes a day of vigorous aerobic exercise like walking or jogging, or play various sports. Strength training for 20 minutes 3 times a week is also helpful.

Take Setria. Taken daily, it will help provide the Glutathione your body needs to keep your body healthy, boosting your performance and preventing disease and aging.

You can find Setria and other L Glutathione products  at IHERB.COM

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Neprinol - Potent Strong Effective Systemic Enzyme

Cleaning Our Blood

The goal with systemic enzymes is to create a healthy blood flow by removing the excess fibrin which forms in the tissues, blood and throughout the body as we age - noticeably in our 40’s and 50’s since our natural production of enzymes decreases. Also for those of us who's digestion is not working optimally there may be large particles of protein floating in the blood, and systemic enzymes can break these down small enough to be filtered out. Fibrin and debris in the blood can clog arteries,  and lead to inflammatory conditions such as chronic pain, chronic fatigue, cardiovascular issues, autoimmune disorders, sclerosis and inflamed joints etc. This is the reason many adults are put on blood thinning medications.

Obviously it is not helpful if we are also eating the Standard American Diet; but in any case top quality systemic enzymes such as Neprinol can be very beneficial.

We have recently switched from Vitalzym to Neprionol which contains 10 times more active ingredients such as:

Nattokinase and Serrapeptase - These break down fibrin and are the most potent fibrin-degrading enzymes helping to reduce blood clots, unclump platelets and digest scar tissue.

Bromelain - Also helps reduce fibrin and increases the conversion of plasminogen into plasmin; but does not dissolve fibrin clumps that have already formed.

As the blood begins to thicken with age, our blood pressure can increase putting a strain on our arteries. Reducing the concentration of fibrinogen in the blood can lead to the reduction of arterial plaque and blood clots.

For this reason keeping our blood clean is vitally important to take the strain off the arteries and to improve circulation into the very tiny capillaries so that all the vitamins, minerals, stem cells and nourishment can more easily reach tissues needing healing and repair.

NOTE: Consult your healthcare professional before taking Neprinol or systemic enzymes if you are a hemophiliac or on drugs for blood coagulation such as prescription blood thinners i.e. Coumadin and Heparin, and others, because the enzymes in Neprinol can cause the drugs to work better and your medications might thin the blood too much.

Consult your physician if you are pregnant or breastfeeding.

My Personal Experience

I have used a synergistic blend of systemic enzymes for 10 years now ever since I had my blood viewed live under a microscope. The clumping platelets and fibrin build up was quite significant and I was only 45 years old at that time with a diagnosis of pre-cancer of the liver. I started with many supplements including systemic enzymes to digest the debris and fibrin in my blood. Two months later, the microscopic view of my blood was significantly improved and I no longer had the pre-cancerous condtion. I did take triple the dosage of systemic enzymes at first to speed up the serious conditions I had at the time. My holistic medical doctor and I agreed upon this higher dosage as I was on the fast track to  heal a very ill body as I had been suffering with chronic fatigue, systemic candida and significant body pain for over twenty years. All a memory now !

I remember how revealing it was viewing my blood under that microscope as my doctor showed me the excess clumping of platelets, oxidative stress and the significant increase in fibrin tissue. As my blood values improved, symptoms were alleviated and I lowered the dosages of systemic enzymes.

Keeping The Blood Clean

I still continue to have my blood viewed every so often with the dark field analysis. Two winters ago I chose to stop the systemic enzymes and 6 months later the microscope revealed my platelets were beginning to clump slightly, so I have chosen to stay on a daily regime of a low dosage, 4 capsules in the early am. I am currently 55 years old and this is often needed at this age to maintain healthy fibrin levels.

Excess fibrin develops as we age. We are born with a finite amount of enzymes which digest and dissolve the fibrin naturally. If we have lived our life eating mostly plants (fruits and vegetables which contain rich sources of enzymes), and little animal products, we may have adequate enzymes to last us our entire lifetime.

Since most of us have lived on cooked and processed foods, the enzymes we were born with have been used up by our late 20’s. As we age the body’s ability to manufacture enzymes diminishes. However, when we consume raw plants and algae, these naturally contain enzymes to digest our meals which will support keeping the blood cleaner.

Clogged Arteries and Capillaries
Sclerosis or Fibrosis
Oxidative stress
Inflammation

The first thing systemic enzymes offer is the digestion of fibrin that may help with sclerosis or fibrosis which is hardening of bodily tissues and organs, clogged arteries and capillaries, oxidative stress, sticky platelets which often develop into pain and inflammation in the body. The goal is to improve blood viscosity so it more resembles a clear running brook as opposed to a swamp.

Nattokinase is one of these fibrin digesting enzymes derived from fermented soybeans enhancing the body’s ability to dissolve blood clots and maintain blood viscosity and cardiovascular health. Serrapeptase is a protein-degrading enzyme derived from a species of bacteria known as Serratia Mercesans originally found in the intestines of silkworms and is a  major enzyme with an anti-coagulating function necessary to dissolve arterial plaque and fibrin, breaking down blood clots as well. These two combined work remarkably well in a synergistic blend of bromelain, protease and lipase.

Why is Neprinol More Effective than other brands?

Neprinol starts off with at least 10 times more of these fibrinolytic enzymes than any other brand we have looked at. Two of these enzymes are nattokinase and serrapeptase.

Neprinol contains a potent synergistic blend of…

• Serrapeptase- breaks down blood clots and arterial plaque
• Nattokinase- maintains blood viscosity and cardiovascular health
• Lipase- digests fat in the blood stream and converts it to energy
• Protease- supports a healthy immune system
• Amla- maintains normal acid and pH balance in nerves, brain and hair           tonic
• Papain- expedites healing of bruises and tissue injuries
• Bromelain- helps maintain healthy skin
• Rutin- builds strong capillaries and connective tissue
• Coenzyme Q10
• Magnesium
• 
  

Many systemic enzymes have very little serrapeptase and nattokinase in them and these ingredients should be at the top of the ingredient list.

Systemic Enzymes are used for ~

• Digesting debris from the cardiovascular system
• Unclumping platelets
• Reducing chronic Pain
• Arthritis – Fibromyalgia
• Sclerosis
• Autoimmune Diseases
• Cleaning debris in the blood
• Liver function
• Inflammatory conditions
• Scar Tissue
• Clogged arteries – poor blood circulation
• Post – Operative Scarring
• Chronic fatigue
• Joint Function
• Fibrosis of organs

~~~~~~~~~~~~~~~~~~~

What Else Can I do To Cleanse My Blood?

Plants naturally contain enzymes. When we eat them, they digest easily because they contain their own enzymes. When we eat raw vegetables and some fruits, the digestive organs i.e. liver, gall bladder, kidneys and intestines are not put under stress as they are when we eat meat, poultry, dairy and the like. This is why eating more vegetarian meals is recommended.

Dosages

How much to use is a personal decision.
Depending on age and health conditions everyone’s dosing is a little bit different.
Consider discussing the following with your healthcare expert.

For some people, starting with 3 capsules 3x per day or 5 capsules 3x a day, for one or two months (depending on the recommendation of your nutritional consultant) has been quite effective to reduce the fibrin tissue and clean the blood and unstick the platelets. Once symptoms improve dosages are reduced and eventually as low as a few capsules daily are taken for maintenance.

Other people choose to start slowly with 2 capsules 2x a day and then build up to higher dosages. The older generation usually have more cardiovascular issues and more fibrin and debris in the blood especially those who have been eating sugary diets, animal based diets and less raw fruits and vegetables.

To Purchase>>  

The Best “Whey” to Nutrition

Protein seems to be the latest sweetheart in nutrition and dieting; in recent years, we have all been bombarded with ads for high-protein snacks and quick-and-easy protein shakes. Is protein just a fad, though? It’s not likely, as this ingredient category has rightly earned its all-star status. Although a huge part of protein’s role in the body is muscle maintenance, protein has several other crucial responsibilities in the body.

Why Does The Body Need Protein?
Besides muscle building and weight management, protein is involved in the formation of tendons, organs, skin, hormones, enzymes and neurotransmitters, and has several specific health benefits. Protein contains lactoferrin, beta-lactoglobulin, alpha-lactalbumin and immunoglobulin, all nutrients that help to lower blood pressure and blood sugar, to reduce symptoms of stress and depression, and increase mineral bone density (1).

Despite the other health benefits of protein, the health and fitness industry may be on to something with its promotion of protein. After all, protein increases strength, muscle gain and aids in healthy weight management (2).

In fact, protein can boost metabolism by up to 100 calories per day, and since it is the most filling macronutrient, it helps people consume as much as 441 fewer calories per day while still feeling full. This is the result of appetite-reducing hormones produced by proteins like GLP-1, PYY, CCK, and also the reduction of the hunger hormone Ghrelin. Just 20 g of protein per shake is enough to benefit from these hunger-reducing effects (2).

A study showed that eating protein for 25% of daily calories cut cravings by 60% and reduced late-night snacking by 50%. Studies have also shown that replacing other sources of calories with whey protein combined with lifting weights can lead to weight loss of up to eight pounds while increasing lean muscle mass. Since muscle burns more calories than fat, muscle gain helps to speed up the metabolism. The body also requires more calories to digest and metabolize protein because of the thermic effect of food, burning 15–30% of protein calories during digestion versus 5–10% of carbs and 0–3% of fats.

Not only does protein help stave off hunger, but its role in the production of lean muscle mass helps keep weight off. Protein is essential in the weight loss process because when you lose weight without adequate protein consumption, you burn muscle as well as fat, therefore slowing down the metabolism and making it easier to regain the weight. Studies have shown that a daily protein shake can make muscle maintenance up to three-and-a-half times more efficient. Other research has shown that those supplementing with protein during weight loss only regained 9% of their weight, whereas those who did not supplement with protein regained up to 23%.

How Much Protein Do We Need?
The recommended minimum dose of protein is 0.34 g per pound of body weight, or between 25 and 50 g per day. However, the typical required amount of protein is 1 g of protein per pound body weight. Athletes and bodybuilders require even more protein, anywhere from 1.3 to 1.5 g of protein per pound body weight (2).

Although protein has many positive health benefits, excess protein is not necessarily beneficial to health. In a study of elderly individuals who were already consuming adequate protein, there was very little growth in muscle mass, suggesting that protein supplementation is most beneficial in the presence of a dietary deficit in this group. In addition, gratuitous protein still provides excess calories, which could lead to weight gain (2).

This is the most common negative effect of protein, but in some people, eating too much can cause digestive problems like nausea, flatulence, diarrhea, pain and cramping. Contrary to popular belief, protein has not been found to contribute to kidney damage, but those with current kidney or liver issues should consume lower amounts of protein (2).

Types of Protein
Protein supplements come from one of two sources: animal or plant protein. Whey and casein, the two main animal proteins, are different yet complementary. They tend to have greater protein benefits and taste, but plant-based proteins, including soy, hemp, rice, and pea, have their own nutritional benefits and can be good alternatives for those maintaining a vegan, vegetarian or lactose-free diet (3).

Whey. Whey protein, made from the liquid part of milk separated out in cheese production, is one of the best-studied supplements on the market. The most popular type of protein, whey tastes good and is a good value for the price. It has been found to promote immune health and weight loss and to suppress hunger.

Whey stimulates growth in humans. After all, 60% of breast milk is whey to stimulate healthy growth in babies, compared to only 20% in cow milk. This is because whey contains all essential amino acids, including branched-chain amino acids (BCAAs), which promote muscle growth. Among these BCAAs is leucine, the most anabolic growth-promoting amino acid. One study found that whey was three times more effective at maintaining muscle during weight loss compared to soy protein (3, 4).

The main difference between whey and another animal-based protein, casein, is that whey is absorbed quickly by the body. This allows whey’s muscle production benefits to begin quickly after consumption (3, 4).

Whey protein also comes in three forms with different benefits and tastes: concentrate, isolate and hydrolysate. Whey concentrate is anywhere from 70–80% protein. It has several dietary benefits because it retains most of the nutrients found in whey. It also has lactose (milk sugar) and fat, giving it a good taste, and these little amounts of fat and sugar are very small relative to daily intake. Whey isolate, on the other hand, is greater than 90% protein. Much of the lactose and fat is removed in production, along with several of the other nutrients. This keeps carbs and fat low, but creates a different taste and thinner consistency. Whey hydrolysate is predigested so that it absorbs faster, resulting in a 28–43% increase in insulin spike compared to isolate (3, 4).

Casein. Casein, another form of milk protein, differs from whey in its absorption rate. Like whey, casein contains all essential amino acids, promotes muscle production, and is tasteless when unsweetened or unflavored. Unlike whey, however, casein is absorbed slowly and creates an anabolic environment for muscle growth and maintenance. Casein is not readily soluble and forms micelles that slowly increase its solubility in water, therefore allowing it to be absorbed over a long period of time. In addition, casein experiences a delay in being transferred from the gastrointestinal tract to the blood, increasing absorption time as well (3, 4).

In one study, researchers gave subjects 30 g of either whey or casein and measured the anabolic and catabolic effect for seven hours after the meal. Those who consumed casein experienced a prolonged increase in blood amino acids that resulted in a 34% lower rate of protein breakdown, while those who consumed whey had no difference in muscle breakdown. Although whey may have created more muscle stimulation in the few hours immediately following supplementation, the net protein balance was more positive for casein after more time (3, 4).

Results like these support that although whey and casein can be beneficial on their own and will have the same net effects, together they may achieve an even better effect, maximizing the stimulation of muscle growth and minimizing breakdown.

Plant-based proteins. Plant-based protein, good alternatives to whey and casein for those with dietary restrictions, work through different channels than their animal-based counterparts. The most popular plant-based proteins are soy, hemp, rice and pea, but there are many on the market.

Soy protein, just like whey and casein, contains all essential amino acids. It also has soy isoflavones, which have antioxidant benefits. Although a good alternative to whey and casein, soy protein has a characteristic taste that can be difficult to mask with sweeteners. Hemp protein is high in omega-3 and omega-6 fats, but low in the essential amino acid lysine, as is protein from rice. Pea protein is low in the non-essential amino acids cystine and methionine (3).

If these proteins are being used supplementally and are not the only form of protein consumption, then these nutritional deficiencies are inconsequential. Some brands of these proteins, however, combine several of these plants to complement each other’s amino acid profile. Although made of different nutrient profiles promoting a host of different benefits, plant-based proteins are a good alternative to animal-based proteins for those with dietary restrictions (3).

When Should Protein Be Consumed?
Timing can be very important to maximize the benefits of supplements, and protein is no exception. However, the optimal time to take protein varies based on the type. Because of its absorption speed and short-term benefits, whey can have the biggest impact just before and after a workout. These effects are short-lived, however, and a meal should be eaten within an hour of a post-workout protein shake. Whey may also be taken in the morning to quickly spur protein maintenance.

Casein, whey’s slow-acting counterpart, is best to take right before bed. This will promote a muscle-preserving environment throughout the night while no calories are consumed. When combining whey and casein, the ideal protein combination, supplementation an hour before and an hour after a workout allows the body to take advantage of both the immediate and prolonged benefits. Although muscle synthesis is at its peak after training, studies have found that the intake of protein is more important than the timing, so taking protein at other times is still better than forgoing it altogether (3, 4).

Check the Labels!
It is very important to read the nutrition facts when choosing a brand of either animal- or plant-based proteins because some supplements have additives like sugar and other sweeteners. Supplements can either have artificial sweeteners, natural sweeteners, a combination of the two, or neither. Although the flavoring has no effect on the nutritional value of the protein, it can add extra calories.

YOU can find Whey Protein and Plant Based Protein supplements at IHERB.COM

References
1. K. Gunnars, “Whey Protein 101: The Ultimate Beginner’s Guide,” www.authoritynutrition.com.
2. A. Petre, “How Protein Shakes Help You Lose Weight and Belly Fat,” www.authoritynutrition.com.
3. M.G. Taylor, “Choosing a Protein Powder,” www.nutritionexpress.com.
4. J.S. Volek, “Whey vs. Casein Protein,” www.nutritionexpress.com.

Why Aloe Vera, and How?

Aloe vera is a popular category, well known for its topical applications but more recently gaining popularity as a beverage, with brands of aloe vera drinks popping up in grocery and convenience stores throughout the country. Mainstream consumers may be vaguely aware of the health benefits of drinking aloe vera, intrigued by its presence beside their favorite organic iced teas, but the keen natural shopper understands the beverage does not necessarily provide the same benefits as its dietary supplement counterpart.

However, even as a dietary supplement, the aloe vera question is not so cut and dry. Juice, gel or capsule? Inner fillet or whole leaf? These options can confuse potential customers. Here are some things to keep in mind when helping consumers choose the right aloe vera product. We’ll also review the evidence for its applications so that customers can understand why they should be taking aloe vera.

Format
Gel. When someone types in “aloe vera gel” into Google, this will likely refer them to topical gels used to soothe sunburns and moisturize dry skin. Clearly, formulas designed for topical use should not be ingested; however, some manufacturers sell aloe vera gel that is good for both dietary and cosmetic purposes. These are often made from the inner leaf of the aloe vera plant separated from the outer rind and the latex; a yellow substance between the rind and inner leaf which contains aloin, the laxative component of aloe vera. Once separated, it is cold-pressed to make it drinkable. Some may contain the pulp of the original plant, while others will use thickening agents.

Juice. Most aloe vera juices are made from the whole leaf — inner filet, aloe latex and all. Rinds and excess aloin found in the aloe latex is filtered out, reducing the aloin content, a powerful laxative, to its safe level of one part per million. Juices have a thinner consistency to gels, but they also differ functionally. The aloin content of the juices made from the whole leaf makes it more beneficial to those seeking to support digestive health. Juices and gels made only from the inner fillet will have nutrients that support health in different ways but their lack of aloin won’t do as much to support regularity.

Capsules. You likely also stock your shelves with aloe vera capsules, which is another viable way to supplement with aloe. Some may simply not like the taste of aloe juice or gel, which are naturally bitter. While it is often recommended to mix the suggested dosage with another liquid, many may find capsules to be a simpler solution. The aloe vera extract in the capsule may also be accompanied by another valuable nutrient or herb, adding extra support.

Digestive Health
As mentioned earlier, aloe vera’s aloin content can support digestive regularity due to its laxative effect, which is mild and safe when filtered down to one part per million. It is, however, unwise for anyone to consume aloin at high doses, directly from the plant, for example, as the laxative effect will be powerful and dangerous, with painful cramps (1). While this makes aloe vera a tool for cleansing, its effects on digestive health go beyond this. Studies have shown that supplementing one’s diet with aloe vera can positively affect the microbiome of the gastrointestinal tract by not only supporting the proliferation of good bacteria but inhibiting the growth of harmful bacteria.

One in vitro study found that at a certain concentration, aloe vera juice promoted the growth of Lactobacillus acidophilus, L. plantarum and L. casei, made evident by a fall in pH and an increase in acidity (2). However, at much higher concentrations, growth was discouraged. Researchers concluded “Aloe vera juice or gel at a particular concentration could possibly be used in combination with probiotic Lactobacillus strain(s) as a combinational therapy for gastrointestinal disorders and cardiovascular diseases” (2).

A different short term study investigated the antibacterial effect of aloe vera gel extract on Lactobacillus spp. and Streptococcus mutans. Results showed that aloe vera significantly reduced the number of Lactobacillus spp. but not Streptococcus mutans (3). A similar effect was observed in an in vitro study on the antibacterial activity of aloe vera on a bacterial strain of Helicobacter pylori, which is isolated to the Abruzzo region in Italy. Results of that study showed that inhibitory concentrations of aloe vera were comparable to those of bactericides, with 50% of detected strains inhibited in their growth (4).

Considering the trending category of probiotics, aloe vera can be an excellent complement for shoppers of probiotic products in the way it may facilitate the growth of good bacteria and protect against harmful bacteria.

Immune Health
Aloe vera’s active components include glycoproteins and polysaccharides. When people use aloe vera to sooth sunburn, glycoprotein speeds the healing process by easing pain and inflammation, while the polysaccharides stimulate skin growth and repair. When consumed orally, these components stimulate the immune system (1). For example, an animal study observed how polysaccharides from aloe vera would affect stress-induced immunosuppression in mice. Results showed that the polysaccharides ameliorated the chronic stress-induced immunosuppression in a variety of ways, including reducing body weight loss and restoring the activities of lymphocytes, T cell proliferation and antibody production (5). Considering how chronic stress is not uncommon in our daily lives, affecting our immune system and making us more susceptible to illness, aloe vera may be one way for your customers to reinforce their defenses.

Much of its immunomodulatory effect is likely accomplished by controlling inflammation. Aloe vera gel for example downregulates lipopolysaccharides-induced inflammatory cytokine production (6). Antioxidants also play an important role in our health, scavenging free radicals that cause oxidation. Aloe vera is rich in antioxidants, including alpha-tocopherol, carotenoids, vitamin C, flavenoids and tannins (6). It should be noted that the whole leaf will provide the greatest concentration of antioxidants as the leaf’s skin has exhibited in vitro the most antioxidant activity.

Blood Sugar
While using aloe vera does not cure or treat disease, prediabetics and diabetics in some studies have exhibited positive results from supplementation. In one randomized controlled trial, for example, aloe vera gel reduced body weights, body fat mass and insulin resistance in obese prediabetics and early untreated diabetics (6). A meta-analysis of randomized controlled trials studying the plant’s effect on prediabetics and untreated diabetics reported that aloe vera was superior to placebo in reducing fasting blood glucose levels, though saw no significant changes in insulin concentration (7). The same meta-analysis also found that aloe vera was superior to placebo in reducing serum triglycerides as well as reducing LDL cholesterol levels (bad cholesterol) while increasing serum HDL (good cholesterol) (7).

It should be noted that not all studies are conclusive on the benefits of supplementing with aloe vera and the plant deserves and requires more, and better designed, randomized controlled trials to truly understand its potential. However, considering the research that does exist, and its traditional usage, aloe vera can be an excellent product for many customers if they understand what they are buying. 

YOU can find aloe vera and probiotics supplements at IHERB.COM

References

1. https://umm.edu/health/medical/altmed/herb/aloe
2. R. Nagpal et al. “Effect of Aloe vera juice on growth and activities of Lactobacilli in-vitro.” Act Biomed. 83(3): 183-188. 2012.
3. T. Prueksrisakul et al. “Effect of daily drinking of Aloe vera gel extract on plasma total antioxidant capacity and oral pathogenic bacteria in healthy volunteer: a short-term study.” J Compliment Integr Med. 12(2): 159-164. 2015.
4. L. Cellini et al. “In vitro activity of Aloe vera inner gel against Helicobacter pylori strains.” Lett Appl Microbiol.59(1): 43-48. 2014.
5. Y. Lee et al. “Modified Aloe Polysaccharide Restores Chronic Stress-Induced Immunosuppression in Mice.”Int J Mol Sci. 17(10). 2016.
6. R.H. Maharjan and L.P. Nampoothiri. ” Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review.” J Tradit Complement Med. 5(1). 2015.
7. Y. Zhang et al. “Efficacy of Aloe Vera Supplementation on Prediabetes and Early Non-Treated Diabetic Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.” Nutrients. 8(7): 388. 2016.