Heart health supplements

Heart health supplements: Which ones really work

First, let's set it straight. Heart health supplements are special extracts from plants and animals which are consumed in much higher quantities, than they could ever be acquired through regular diet.

On the other hand, herbs are pure extracts of mother nature in its natural form, such as hawthorn and garlic. 

Good example of supplements are fish oil, DIM or creatine.

Now, when we said that, we can continue. 

Supplements have some qualities that herbs lack and vice versa.

On the other hand, supplements for heart disease are often much stronger than the herbs because of which caution should be advised while using some of them, especially if you are already taking prescription drugs.

HOW THESE SUPPLEMENTS WORK

Most of these heart disease supplements, are strong antioxidants. They can neutralize free radicals, regenerate other antioxidants (ALA) and reduce the risk of inflammation thereby preventing tissue damage. 

Others may improve heart function (Coenzyme Q10), lipid levels (Fish oil) or hormonal balance (Vitamin D and DIM).

LIST OF HEART HEALTH SUPPLEMENTS

Fish oil supplements are the second most sold supplements in the world, right next to the multivitamin. They can lower LDL cholesterol and triglycerides, raise HDL cholesterol, stabilize blood clotting mechanisms, reduce blood pressure and the risk of heart attack.

While buying fish oil supplements, you have to take in a considiration the purity, potency and place of origin.

Coenzyme Q10 is fat-soluble, vitamin like substance found in mitochondria, where it is used for production of ATP. ATP is a molecule which carries energy for heart function. It has been proven connection between lack of coenzyme Q10 and heart disease.

Levels of this antioxidant diminish with age. It is also, one of the two best supplements for heart disease since it may improve ejection fraction of the heart muscle.

Acetyl l carnitine is an amino acid which is naturally produced in the body. It is more bioavailable and more useful than L-carnitine.

It is one of those heart health supplements which is also great for the brain function since it can cross the blood-brain barier. Heart muscle tends to be particularly vulnerable to carnitine deficiency because of its high energy requirements. 

Alpha lipoic acid or ALA is fatty acid found inside every cell in our body. It is a powerful antioxidant that regenerates other antioxidants.

It is one of heart disease supplements which is also great for the liver and blood sugar control. However, its true power comes from the ability to regenerate other antioxidants, in the body.

ALA and carnitine supplements are more suited for people above the age of 40. 

Lycopene is another great antioxidant found in fruits and vegetables but is mostly consumed via tomatoes and tomato based products. In one study,women with the highest concentrations of lycopene in their blood, had 50 % reduced risk of heart disease.

Because of this study, it has gained a lot of attention. It has become one of the most interesting heart health supplements.

Astaxanthin is a carotenoid like lycopene, something like lycopene's big brother but it is much stonger antioxidant. Unlike some carotenoids, it is not converted to vitamin A which can be toxic, in high concentrations.

Astaxanthin reduces arterial plaque formation, protects cells from oxidative damage and the skin from UV light. It may even help increase endurance and reduce the risk of hypertension and stroke.

Vitamin D is a special kind of vitamin which is actually a hormone. It is also the only kind of vitamin, you should take as a supplement. All other vitamins you can get from foods, even if your diet is not the most healthiest. Although it is found in some foods, the amount is very small.

Only real sources of vitamin D, are the sun and the supplements. That being said, the list of benefits is getting bigger every day, includingvitamin D benefits for treating heart disease.

Salicin is natural compound found in higher quantities, in several herbs. It is metabolised into salicylic acid, in the stomach which is also found in aspirin.

Salicin is natural blood thinner and anti-inflammatory compound which can be used in treatment of heart disease. However, it is most effective for lowering the risk of heart attack, by reducing formation of blood clots.

Diindolylmethane or simply DIM is one of those supplements which can be extremly helpful, if heart disease was caused by unbalanced sex hormones. By improving testosterone to estrogen ratio, heart function also improves. However, diindolylmethane benefits don't stop there. 

TIP

Taking few of these heart health supplements together with the most useful supplement for heart disease, fish oil, can have more stronger effect.

WHERE TO BUY SUPPLEMENTS

I tried a lot of supplements, before I found couple of them that really work for me. During that time, I always searched for online web store with whom I could save few bucks. 

I've come to the conclusion that iherb.com is best choice. If you decide to buy from iherb use in shopping cart coupon welcome5 for 5$ off your first order.

CONCLUSION

First of all, same as with herbs, food and healthy diet are the foundation of your heart disease treatment. After you establish healthy eating habits, you can consider about adding supplements to your diet.

If you ask me which supplements are the most effective for treating heart disease, I would say fish oil, alongside Coenzyme Q10. Although other heart disease supplements can help, they still aren't the first choice for treating heart disease.

Only exception would be vitamin D3 and DIM. Vitamin D3 may lower blood pressure due to its effect on renin-angiotensin-aldosterone system, while diindolylmethane may have positive effect on the heart function, by improving T to E ratio. 

Before taking any of these heart health supplements consult with your doctor, for possible side effects or interactions.

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The Buyer's Guide to iHerb Codes 

iHerb Inc. is an online store for dietary supplements and natural health products. Being one of the largest company in this industry, iherb com is capable of selling its products at very low and competitive prices, while offering extra discounts through their iherb coupon system for first-time customers.

I've been their regular customer since 2008. iHerbs great customer service, low prices, and their huge range of products make an iHerbs online store for dietary supplements unbeatable. Additionally, iHerb Coupon Code program is one of the best for earning rewards. 

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Differences Between Conventional and Ubiquinol CoQ10

Written by Andrew Shea•Reviewed by Robert Barry, PhD

Millions of Americans take a CoQ10 supplement to support heart health. Many are surprised to learn that Coenzyme Q10 actually exists in two main forms with important differences.

Conventional CoQ10, technically known as ubiquinone, is the oxidized version of the nutrient. We get some of it from the food we eat but most of our supply is made naturally inside our bodies.

More than 90% of the total CoQ10 in the blood of a healthy young adult is in the Ubiquinol form. 1

Before it can do many of the wonderful things people associate with CoQ10, the conventional form of CoQ10 needs to be converted by our bodies into a more advanced form called Ubiquinol CoQ10.2 

This conversion into Ubiquinol (pronounced “you-bik-win-all”) becomes more difficult to complete as we get older or when we have certain health conditions.3 4

Turning Conventional CoQ10 into Ubiquinol CoQ10

Ubiquinol CoQ10 has two special traits missing from its less-advanced cousin: hydrogen molecules and extra electrons.5 They can make a big difference in the nutrient’s ability to move through the blood and be absorbed into cells. The two traits also impact antioxidant activity and play a critical role in making cellular energy.6

Our bodies must convert conventional CoQ10 into Ubiquinol before it can be used to create cellular energy.

Unfortunately, turning conventional CoQ10 into Ubiquinol isn’t easy for many of us as we get older. 

Imagine me as a healthy 18 year old needing to push several heavy balls up a hill. Young and carefree Andy has little trouble getting each ball to the top and returning for another one. He barely broke a sweat.

Now imagine me as a 65 year old trying to do the same thing. Though wiser and more mature, 65 year old Andy has a difficult time with this repeating activity. Each trip becomes slower and requires increased recovery time.

A similar uphill process happens in our bodies with conventional CoQ10 when we attempt to convert it into Ubiquinol.

Why the Need to Change into Ubiquinol? 

Our most important organs and muscles – the brain and the heart, for example – require massive amounts of cellular energy to function at optimal levels. To make this energy, we need CoQ10 in its Ubiquinol form.  

Starting around the age of 30, our bodies have a harder time changing conventional CoQ10 into the more advanced Ubiquinol form, impacting our bodies' supply of cellular energy.

Inside tiny cellular power plants called mitochondria, Ubiquinol CoQ10 uses its two electrons in a very specific way to help convert food to a type of fuel (called ATP) needed by our bodies.

Young, healthy people like 18 year old Andy easily turn ubiquinone into Ubiquinol CoQ10.

But starting around the age 30 and especially after 40, our ability to turn that conventional CoQ10 into the desirable Ubiquinol becomes harder and less efficient. This has an impact on the amount of cellular energy available for our organs to use.

Ubiquinol CoQ10: Another Important Difference

So far we’ve established that the Ubiquinol form of CoQ10 plays a critical role in producing cellular energy needed by important organs such as the heart and the brain. We’ve also covered how, starting around the age of 30, our bodies have a harder time changing conventional CoQ10 into the more advanced Ubiquinol form, impacting our bodies’ supply of cellular energy.

But there’s something else that makes Ubiquinol CoQ10 special.

Unlike conventional CoQ10, Ubiquinol is a very powerful antioxidant by virtue of its two extra electrons. Those electrons are important because they hold the key to neutralizing substances called free radicals.

Free radicals are harmful because they are constantly looking to steal electrons wherever they may be found, including DNA, proteins and lipids. Removing an electron oxidizes the molecule (oxidative stress) and can cause damage that impacts our health. 

The Ubiquinol form of CoQ10 doesn’t mind giving up an electron to neutralize a free radical that might have otherwise caused some metabolic trouble.

What’s more, Ubiquinol CoQ10 is one of the few antioxidants that work not just in the fatty parts of our body (such as cell membranes and LDL cholesterol) but also in the mitochondria where energy is manufactured.7 Like car engines produce exhaust, the mitochondria have their own form of exhaust filled with free radicals.

Ubiquinol is the only form of CoQ10 capable of protecting the mitochondria and their lipid membranes from free radical attack.

What’s The Connection to CoQ10 Supplements?

Plenty of Americans take CoQ10 supplements to assist in creating cellular energy that, among other things, is essential in supporting a healthy heart. That’s an important step in promoting good health, but the type of CoQ10 being consumed is critically important.

The energy demands of the human heart are among the highest in the body. This important muscle needs Ubiquinol CoQ10 to function optimally.

Many of the people who take a CoQ10 supplement are taking it in its conventional form. Conventional CoQ10 is fine if you’re a healthy 20-something because your body can easily convert it into Ubiquinol.

Unfortunately, millions of Americans over the age of 30 are unknowingly doing themselves a disservice when they consume CoQ10 in its conventional form. They receive limited value because they may be unable to convert much of the conventional CoQ10 into heart-healthy Ubiquinol.

So what happens when a person takes conventional CoQ10 instead of Ubiquinol?

Sadly, only some of that conventional CoQ10 makes it into their blood, and even less is converted into the desired Ubiquinol form of CoQ10.

If you’re age 30 (or better!) and taking CoQ10 to support your health, be sure to take it in the advanced Ubiquinol form so your body enjoys the maximum benefit possible.

You can find over 170 Coenzyme Q10 products at IHERB.COM 

References

1. Tang PH, Miles MV, DeGrauw A, Hershey A, Pesce A. HPLC analysis of reduced and oxidized coenzyme Q(10) in human plasma. Clin Chem. 2001 Feb;47(2):256-65.
2. Tomasetti, M, Alleva R, Borghi B, Collins AR. In vivo supplementation with coenzyme Q10 enhances the recovery of human lymphocytes from oxidative DNA damage. FASEB J. 2001 Jun;15(8):1425-7.
3. Wada H, Goto H, Hagiwara S, Yamamoto Y. Redox status of coenzyme Q10 is associated with chronological age. J Am Geriatr Soc. 2007 Jul;55(7):1141-2.
4. Niklowitz P, Onur S, Fischer A, Laudes M, Palussen M, Menke T, Döring F.  Coenzyme Q10 serum concentration and redox status in European adults: influence of age, sex, and lipoprotein concentration.  J Clin Biochem Nutr.  2016 Jan.  Online publication.
5. Frei B, Kim MC, Ames BN. Ubiquinol-10 is an effective lipid-soluble antioxidant at physiological concentrations. Proc Natl Acad Sci U S A. 1990 Jun;87(12):4879-83.
6. Beamer WM and Deamer DW. Energy from Chemical Bonds: The aerobic mode. In: The World of the Cell, 2nd Ed., The Benjamin Cummings Publishing Company, Inc, Redwood City , CA., pps. 275-313.
7. Forsmark-Andrée P, Lee CP, Dallner G, Ernster L. Lipid peroxidation and changes in the ubiquinone content and the respiratory chain enzymes of submitochondrial particles. Free Radic Biol Med. 1997;22(3):391-400. 
8. Wada H, Goto H, Hagiwara S, Yamamoto Y. Redox status of coenzyme Q10 is associated with chronological age. J Am Geriatr Soc. 2007 Jul;55(7):1141-2.
9. Niklowitz P, Onur S, Fischer A, Laudes M, Palussen M, Menke T, Döring F.  Coenzyme Q10 serum concentration and redox status in European adults: influence of age, sex, and lipoprotein concentration.  J Clin Biochem Nutr.  2016 Jan.  Online publication.
10. Miles MV, Horn P, Milesc L, Tanga P, Steele P, DeGrauwa T. Bioequivalence of coenzyme Q10 from over-the-counter supplements. Nutr Res.  2002:22(8):919-929.
11. Evans M, Baisley J, Barss S, Guthrie N.  A randomized, double-blind trial on the bioavailability of two CoQ10 formulations. Journal of Functional Foods. 2009. 1: 65-73.

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